image
Reach Us +442837180055
SOCIETIES:
mental health, psychiatry and mental health, journals on mental health, mental health journals, journals mental health
journals for mental health, best journals for mental health, mental health journals uk, journals on psychiatry
JOURNAL COVER:
journals of psychiatry, psychiatry journals, asean, journal
Google Scholar citation report
Citations : 2789

ASEAN Journal of Psychiatry received 2789 citations as per google scholar report

ASEAN Journal of Psychiatry peer review process verified at publons
IMPACT FACTOR:
Journal Name ASEAN Journal of Psychiatry (MyCite Report)  
Total Publications 32
Total Citations 16
Total Non-self Citations 12
Yearly Impact Factor 0.053
5-Year Impact Factor 0.104
Immediacy Index 0.000
Cited Half-life 2.7
H-index 3
Quartile
Social Sciences Medical & Health Sciences
Q3 Q2

Abstract

MAST CELL IN AMYGDALE, THALAMUS, HIPPOCAMPUS OF WISTAR RATS AND ITS CORRELATION WITH CORTICOTROPIN-RELEASING HORMONE (CRH) PLASMA LEVEL AND LENGTH OF ACUTE STRESS EXPOSURE

Author(s): Bonaventura Handoko Daeng, Obed Paundralingga, Aris Widodo, Hidayat Sujuti, Karyono Mintaroem, Edi Widjajanto

Objective: Stress increases CRH level in the blood, which then affects the mast cell’s number and function. This study aims to determine whether there is a correlation between the lengths of exposure and changes in the level of CRH and the existence and the activity of the mast cells in the area of amygdale, thalamus and hippocampus in rats exposed to acute stress. Methods: Sixteen rats were divided randomly; 4 in the control group and 12 in the exploratory group. The latter were then equally divided into 3 experimental groups, each consisting of 4 subjects. Each of the 12 rats that belonged to the 3 experimental groups was exposed to stress using the psychological stress device for three different lengths of time; 30, 60, and 90 minutes. The CRH plasma was then examined using enzyme-linked immunosorbent assay (ELISA), mast cells in amygdale, thalamus and hippocampus using the light microscope. Results: There was no significant difference in the number of mast cells, but the ones in the thalamus tended to increase (p = 0.092), compared to the amygdale (p = 0.269) and hippocampus (p = 0.117), in line with the length of the treatment, amygdale (r=0,291, P=0,274), hippocampus (r=-0.250, p=0.350), thalamus (r=0.619, p=0.11) in the response to stress level. Conclusions: There was a significant correlation between the lengths of exposure, the level of CRH with the number of mast cells in the thalamus, but there was no correlation both in amygdale or hippocampus.


PDF

scan code
INDEXATION OF THE JOURNAL
Get the App