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Non-Benzodiazepine Hypnotic Dependence: A Case Report
Author(s):
Amer Siddiq Amer Nordin*, Noor Zurani Md Haris Robson**, Azreen Hashim*, Mohamad Hussain Habil*
Institution(s):
*Department of Psychological Medicine, Faculty of Medicine, University Malaya, 50603 Kuala Lumpur, Malaysia; ** Department of Primary Care Medicine, Faculty of Medicine, University Malaya, 50603, Kuala Lumpur, Malaysia.
Abstract:
Objective:
This case report highlights the abuse and dependence potential of Zolpidem and the risk of life-threatening withdrawal symptoms upon abrupt discontinuation.
Methods:
We report a case of Zolpidem dependence which presented with withdrawal symptoms upon abrupt discontinuation.
Results:
A 32 year old male, who had abused non-benzodiazepine Zolpidem for 6 years presented to the accident and emergency unit with generalized seizures upon stopping Zolpidem ‘cold turkey’. He required admission to the neurology high dependency unit for stabilization of the seizures and was later managed by the addiction team where a tapering dose of benzodiazepine was prescribed.
Conclusion:
This case demonstrates that non-benzodiazepine agents can cause tolerance and dependence, and thus produce withdrawal symptoms upon discontinuation. ASEAN Journal of Psychiatry, Vol.11(1): Jan - June 2010: XX XX.
Keywords: Zolpidem, abuse, dependence, addiction, withdrawal, intoxication
For full article, please download the document, below:
 Non-Benzodiazepine Hypnotic Dependence: A Case Report (format: pdf, size: 300 Kb)
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